PRF Platelet-Rich Fibrin
PRF Platelet-Rich Fibrin
Platelet Rich Fibrin or just PRF is a natural treatment in which your blood is drawn, processed, and then re-injected into your body in specified areas. The process takes PRP (platelet-rich plasma) and is added to a fibrin gel to create the injectable PRF. It has incredible healing properties, supporting cellular regeneration and collagen production in the skin.
The results are healthier, tighter skin with more volume over time. This procedure is one of the best treatments to naturally prevent and treat fine to moderate lines on the face. PRF injections are safe for anyone who wants more youthful-looking skin in areas of the face and neck. PRF injections are also used to stimulate hair growth; therefore they may be a valid treatment for those suffering from hair loss.
PRF can be injected into acne scars, the under eyes, and hollow areas on the face. PRF will add more instant volume through collagen stimulation but it’s a better option if you have deeper wrinkles, hollows, or more advanced signs of aging. PRF is often called a natural filler because it’s highly effective at building volume.
Compared to PRP (Platelet Rich Plasma), PRF has a higher concentration of platelets, fibrin, and white blood cells, along with a small amount of stem cells. The platelets attach to the fibrin network and release the growth factors that are responsible for creating new skin cells, collagen, and blood vessels. The growth factors in PRF are also released much slower than in PRP, which provides the added bonus of a longer lasting anti-aging treatment!
You can see results from PRF in one treatment but it is recommended to complete a courses of treatments. Results can last for up to 6- 12 months or even longer.
Benefits of PRF Injections
- Overall tissue rejuvenation/regeneration
- Reduced appearance of scars
- Improved skin tone and texture
- Minimized pores
- Reduced wrinkles and fine lines
- Brand-new collagen and elastin production
- Natural and chemical-free
- Re Volumizing
Face / Neck / Chest | From €400 |
Eyes | From €300 |
PRP & PRF | From €500 |
Cellular Matrix | €450 |
PRP + PRP + Cellular Matrix | From €900 |
PRF can be injected into acne scars, the under eyes, and hollow areas on the face. PRF will add more instant volume through collagen stimulation but it’s a better option if you have deeper wrinkles, hollows, or more advanced signs of aging. PRF is often called a natural filler because it’s highly effective at building volume.
Compared to PRP (Platelet Rich Plasma), PRF has a higher concentration of platelets, fibrin, and white blood cells, along with a small amount of stem cells. The platelets attach to the fibrin network and release the growth factors that are responsible for creating new skin cells, collagen, and blood vessels. The growth factors in PRF are also released much slower than in PRP, which provides the added bonus of a longer lasting anti-aging treatment!
You can see results from PRF in one treatment but it is recommended to complete a courses of treatments. Results can last for up to 6- 12 months or even longer.
Benefits of PRF Injections
- Overall tissue rejuvenation/regeneration
- Reduced appearance of scars
- Improved skin tone and texture
- Minimized pores
- Reduced wrinkles and fine lines
- Brand-new collagen and elastin production
- Natural and chemical-free
- Re Volumizing
Face / Neck / Chest | From €400 |
Eyes | From €300 |
PRP & PRF | From €500 |
Cellular Matrix | €450 |
PRP + PRP + Cellular Matrix | From €900 |

Frequently Asked Questions
Frequently Asked Questions
Both platelets and fibrin are involved in your body’s natural healing processes, and PRP and PRF both contain higher-than-normal numbers of platelets for enhanced healing action. But there are some important differences between the two products, beginning with how they’re processed
In order to make both PRP and PRF, your blood sample is spun at a high speed, allowing heavier components of your blood to sink to the bottom of the container, while lighter platelets and plasma stay at the top. This process makes it easier to extract only the platelets and plasma — or PRP.
PRF is processed at a slower speed. As a result, the finished product still retains some white blood cells, stem cells, and of course, fibrin. That means there are more carrying healing factors in PRF — specifically, factors associated with platelets, fibrin, and stem cells. The slower speed also has the potential to cause less damage to individual cells, which is especially important when harvesting stem cells for healing.
This might surprise you, given the two products’ names. But because PRP is spun more quickly, many of the platelets can wind up being left out of the final product. The number of platelets will still be higher than what’s normally found in your blood — generally from 3-5 times higher.
However, the slower speed associated with PRF production may allow even more platelets to remain in the final solution. That means it can be an even richer source of platelets.
PRP production uses an anticoagulant to prevent your blood sample from clotting while it’s processed. In PRF production, fibrin (a component of clots) is allowed to form. The final PRF product forms a sort of scaffold or matrix that enables platelets to be released more slowly once they’re injected.
In fact, this is one of the biggest differences in terms of how each product is used: PRP releases more platelets and growth factors more quickly, while PRF releases platelets and growth factors more slowly after injection.
The areas of the face that can be injected with PRF include but are not limited to: cheeks, temporal hollows, tear troughs, nasolabial folds, the jawline, chin, and scalp for hair regrowth. There is a narrow time window of approximately 15-20 minutes until the PRF turns into a gel-like consistency. The full procedure takes approximately 45-60 minutes.
CM-PRP-HA Cellular Matrix® tubes allow the preparation of PRP with a non-crosslinked hyaluronic acid (HA) in a closed-circuit system. Cellular Matrix® technology combines the complementary clinical effects of PRP® and hyaluronic acid (HA), giving better and longer-lasting result.
When PRP and HA are used in combination these effects are enhanced and prolonged. HA creates a bioactive scaffolding in which the platelets progressively release their growth factors. RegenPRP does not negatively affect the mechanical, elastic or viscous properties of HA.
PRF is not a total replacement for fillers, but it will provide natural volume replacement and stimulation over time of natural collagen in the area placed.
When you combine both PRF and dermal fillers, the results are outstanding. While PRF takes time to work and the best result is often up to a year after the initial treatment), whereas the filler is immediate. It can be a personal choice to have a slower more natural regeneration of collagen production.
PRF is obtained from a small amount of your own blood and centrifuging it without an anticoagulant for a very high concentration of platelets trapped in your fibrin matrix. Unlike PRP, PRF contains white blood cells and mesenchymal stem cells from your own blood which means it has much more superior regenerative properties than PRP.
PRF under eye filler is a very natural treatment utilizing your own stem cells and growth factors. Unlike dermal fillers, PRF improves under eye pigmentation and skin firmness/texture/thickness in addition to providing subtle subdermal volume. The results from PRF are always natural, without puffiness or fluid retention.
PRF is not a total replacement for fillers, but it will provide natural volume replacement and stimulation over time of natural collagen in the area placed.
When you combine both PRF and dermal fillers, the results are outstanding. While PRF takes time to work and the best result is often up to a year after the initial treatment), whereas the filler is immediate. It can be a personal choice to have a slower more natural regeneration of collagen production.
PRF (platelet-rich fibrin) is more concentrated than PRP (platelet-rich plasma). Both include platelets, but PRF also offers further benefits which PRP does not, including a higher concentration of platelets with more stem cells because of how the platelets are held for a longer time at the bulge region of the hair follicle.
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*Results and benefits can vary and are different for each individual. Therefore The Laser and Skin Clinic cannot guarantee specific results.